PMID: 18214303
Infect Dis Ther 9 , 657667 (2020)
Cyclodextrin-based delivery systems in parenteral formulations: A critical update review
The most popular GHSs for bodybuilding include: growth-hormone releasing hormones,such as sermorelin, tesamorelin, CJC-1293, and CJC-1295 ghrelin and compounds mimicking its actions,such as lenomorelin, anamorelin, ipamorelin, macimorelin, and tabimorelin growth hormone-releasing peptides (GHRPs), such as alexamorelin, GHRP-1, GHRP-2, GHRP-3, GHRP-4, GHRP-5, GHRP-6, and hexarelin Each of these peptides may stimulate the production and release of HGH, although they do so in slightly different ways
Concurrently, IR induces a state of anabolic resistance, whereby the skeletal muscle becomes less responsive to the protein-synthetic stimulus of both insulin and essential amino acids, further crippling its maintenance and repair capabilities (60, 61)
But because it slows the rate of stomach emptying and alters hunger cues, the first weeks can come with nausea, constipation, diarrhea, reflux, and abdominal discomfort