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In summary, from a clinical point of view, additional mechanistic investigations of the novel natural modulators on melanogenesis are urgently required

Hasta ahora, estudios grandes en humanos no han mostrado un aumento claro del riesgo

The article says protein-based molecules are partially degraded in the infant gastrointestinal tract, which would reduce bioavailability

It's that the pharmacokinetic path from muscle to skin dermis wastes the majority of dosed peptide on systemic distribution that contributes nothing to cosmetic endpoints

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Historical dates, trial results, and approval milestones cited above are based on FDA records and published literature