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Weeks 13 to 16: enhanced effects (1.7 mg per week) The second-to-last escalation step

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3.6 Measuring photochemical immunogenic cell death PDT can induce photochemical ICD through the release or translocation of DAMPs, such as HSP-70, calreticulin, and HMGB1 [2, 3, 5, 8, 12, 13]

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The results suggest that there are beneficial effects on weight and, with that, reductions in insulin dose