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HDACs have distinct distribution patterns in diverse brain regions

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This peptide has been found in the human body, including in blood plasma, saliva, and urine

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As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively