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10.1002/brb3.2177 245 KobayashiY.SugaharaH.ShimadaK.MitsuyamaE.KuharaT.YasuokaA.et al

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Epithalon also reduces intracellular reactive oxygen species, protects mitochondrial function under oxidative stress, and decreases apoptosis markers in aged or stressed models

Western blotting revealed that knocking down CYPOR prevented Nrf2 accumulation and GCLC induction upon NFT treatment (Fig