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Tirzepatide (weekly injectable) Dosing frequency: Once weekly, same day each week Half-life: approximately 5 days (120 hours) Peak concentration: 8 to 72 hours after injection Recommended timing approach: The shorter half-life compared to semaglutide means the end-of-week trough is more noticeable

People who take drops while lying in bed or reclining on a couch almost always swallow the medication prematurely because gravity pulls the liquid backward

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