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While these are different trials with different designs and not a direct head-to-head comparison, the data suggests retatrutide may deliver greater weight loss

It represents the last day the product is guaranteed to be safe for use

Sources Phase 2 Retatrutide Trial (NEJM) Triple hormone receptor agonist retatrutide for metabolic dysfunctionassociated steatotic liver disease Triple Agonism Review (PMC) Triple Agonism Based Therapies for Obesity Retatrutide Game Changer Review RetatrutideA Game Changer in Obesity Pharmacotherapy The Atlantic GLP3 Underground Market GoodRx Retatrutide Availability & Dosage Retatrutide for Weight Loss: Availability, Dosage, and More Phase 3 Trial Update (Clinical Trials Arena) Lillys triple G agonist boasts 28.7% weight loss in Phase III trial Retatrutide FDA Status 2026 Retatrutide FDA Approval Status 2026: Phase 3 Results Update GLP3 Retatrutide FAQ (Expert) GLP3 Retatrutide Peptide Expert FAQ Dr

This comparison summarizes the molecular design, pharmacokinetics, and regulatory landscape distinguishing the two compounds

Supporting Study: Hayes, M

AE were similar between bimagrumab and placebo, although bimagrumab was associated with transiently elevated pancreatic and liver enzymes [97]