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Mitochondria are increasingly recognized not merely as energy-producing structures, but as signaling hubs involved in oxidative balance, cellular adaptation, and stress-response coordination

Calorie restriction and the consequent reduction in food intake can significantly compromise the adequate supply of micronutrients, impacting basal metabolism and immunity

Glucose-independent glutamine metabolism Via tca cycling for proliferation and survival in b cells

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If the goal is muscle support, recovery, skin health, or tissue repair, low protein intake can slow progress