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Obesity management for the treatment of type 2 diabetes

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The researchers showed that FOXO4-DRI treatment induced apoptosis specifically in senescent chondrocytes while sparing healthy proliferating cells, confirming the selectivity mechanism described in the original Baar et al

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Elastin fibers are damaged and have limited capacity to regenerate naturally (adult humans produce very little new elastin after puberty under normal conditions)

Treatment is typically provided through specialist weight management services with defined monitoring and review periods