Coarse-grained molecular dynamics simulations reveal GLP-1R cholesterol binding sites and state-dependent cholesterol binding modes To gain insights into the precise location of cholesterol interactions with the GLP-1R, cgMD simulations were employed to study both active (corresponding to agonist bound) and inactive (apo-) states of GLP-1R in a model mammalian plasma membrane using the latest Martini 3 forcefield and cholesterol parameters (Figure 2A)
10.1111/jfbc.13323 107 PaikraB
L-Carnitine: Natural Fat Burner and Energy Booster Unlike Ozempic, which works as an injectable medication, L-Carnitine is a naturally occurring amino acid that plays a key role in energy production and fat metabolism
doi: 10.1080/21691401.2019.1620248 77 ZhouS
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
Division of Nephrology, Department of Internal Medicine, Thammasat University Hospital, Pathum Thani, Thailand