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By immunohistochemical staining and western blot analysis, an increase in MMP-9 expression in the CS group was observed compared to that in the control group, and pretreatment with GHK-Cu reduced MMP-9 expression compared to that in the CS group (Figures 2AC)

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The intended sample size was approximately 410 patients

-22.5% Avg body weight loss at highest dose (SURMOUNT-1) 96% Lost at least 5% body weight 72 weeks Trial duration Context: Clinical trial participants also received lifestyle intervention (diet and exercise counseling)

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Breastfeeding mothers may also benefit from B12 injections to ensure their babies receive sufficient B12 through breast milk