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Injection logistics: Adding KPV brings the KLOW stack to four vials, four reconstitutions, and four to five injections per day

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Beyond sleep, studies indicate it might be involved in hormone regulation, pain perception, and stress modulation

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(PubMed) Guenther BD, Sheppard CA, Tran P, Rozen R, Matthews RG, Ludwig ML

Moreover, in Vgat-IRES-cre obese mice, only a higher tesofensine dose could suppress optogenetically induced feeding, suggesting that, during obesity, LH GABAergic neurons seem to be hypersensitized