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The Gu syndrome management includes dietary interventions, lifestyle changes, acupuncture, and herbs, and minimal pharmaceutical interventions

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Free radicals are unstable atoms that can cause damage to cells, proteins, and DNA if they accumulate in the body

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In some embodiments, the otic gel formulations or compositions comprises (i) a therapeutic agent, (ii) a gelling and viscosity enhancing agent, (iii) a pH adjusting agent, and (iv) sterile water