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While cross-trial comparisons are limited by differences in patient populations and study duration, the head-to-head percentage is clear: Retatrutides triple-action mechanism has generated the highest average weight loss percentage reported to date for any single pharmacological agent

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Despite attempts to minimize bias through a systematic and comprehensive search strategy, unpublished or negative studies may have been overlooked

PMCID: PMC8978023

Adderall XR lasts around 812 hours, and Adderall IR lasts between 46 hours