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When it comes to treatment goals, the medications fall into two main categories: those targeting type 2 diabetes (Ozempic, Rybelsus, Mounjaro, Victoza, and Trulicity) and those approved for weight management (Wegovy, Zepbound, and Saxenda)

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The use of nalbuphine, a blocker of - and -opioid receptors, also disrupted the effect of GLP-1RAs on reducing TNF- levels, highlighting the essential role of these opioid receptors in the anti-inflammatory effects mediated by GLP-1RAs

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