Intranasal delivery lets the peptide bypass the blood-brain barrier via olfactory transport routes, which speeds its central nervous system effects in animal models
Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
When this is found, consideration should be given to the possibility of any one of a number of rarely encountered conditions such as Peutz-Jehgers syndrome, Laugier-Hunziger syndrome, Bannayan-Riley-Ruvalcaba syndrome, LEOPARD syndrome, and the several syndromes in which lentigines and cardiocutaneus myxomas are found
Sleep apnea Zepbound was approved by the US Food and Drug Administration for obstructive sleep apnea in December 2024, making it the first drug to directly treat patients with the common disorder that causes breathing disruption while sleeping.
10.1111/bcpt.12850 [DOI] [PubMed] [Google Scholar] Hofbauer L
7 Dietary and Lifestyle Considerations to Promote Kidney Health Avoidance of Nonsteroidal Anti-inflammatory Drugs Use of nonsteroidal anti-inflammatory drugs (NSAIDs) for the treatment of pain and inflammation can increase the risk of NSAID-induced kidney damage