Ser/gly pathway metabolites are required for RT recovery in NSCLC To validate the observations in the plasma of patients with NSCLC and confirm our hypothesis of augmented ser/gly pathway dependency, we performed 13 C 6 -glucose tracing and metabolomics analysis in a panel of 5 NSCLC cell lines, i.e., NCI-H1299, NCI-H125, NCI-H1975, Calu-6 and NCI-H520 to identify the RT related metabolic changes
No completed human efficacy trial of the fragment exists
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