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PMID: 9449682

There are two main trials (FIGHT and LIVE trials) demonstrating that treatment with liraglutide increased the risk of adverse heart failure-associated outcomes in patients with heart failure and reduced LVEF [43-45]

Since the cost of these drugs can be prohibitive, these findings could have a major real-world impact, says Mitch Biermann, MD, PhD, an author of the study and an obesity medicine and internal medicine doctor at Scripps Clinic Carmel Valley in California

The UK has its own separate framework following Brexit, with the MHRA providing guidance on research chemical imports

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