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Methotrexate is contraindicated in pregnancy and breastfeeding

It plays a critical role in protecting cells from oxidative stress, supporting healthy detoxification mechanisms, and maintaining overall cellular health

But for some people, the side effect profile makes it unsustainable

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[21] [22] These appraisals set out the structured clinical framework within which approved anti-obesity pharmacotherapy may be offered in the UK

The company previously announced that clinical trial participants lost an average of 17.4 percent of their baseline body weight after 68 weeks of using this new oral formulation