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444 Moreover, the transcriptional complex formed by TAZ and TEAD4 has two binding sites in SOX2 promoter, which in turn facilitates transcription of SOX2, leading to the self-renewal property and maintenance of the cancer stem cell population in HNSCC cells

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The emphasis is on progressive overload systematically increasing the challenge over time which is the fundamental stimulus for muscle preservation and growth

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A skeletal developmental disorder, KBD has been reported in low-selenium areas of China, North Korea, and the Siberian region of Russia, and can be alleviated by selenium supplementation