Both NNC0090-2746 (107) and tirzepatide (63) delivered clinically meaningful improvements in glycemic control and body weight reduction in their phase 1 trials
GLP-1s are generally well tolerated, with most gastrointestinal side effects subsiding over time
These results indicated that GLP-1RAs might play a useful role in the future treatment of PD
N Engl J Med (2015) 372(14):133341
Biopharma PEG supplies polyethylene glycol (PEG) derivatives, monodisperse PEGs, custom PEG derivative synthesis and PEGylation services worldwide, from R&D through GMP commercial quantities, for preclinical, clinical trials, and commercial products for pharma, biotech, medical devices, and diagnostics
Fusion technology, which involves linking a target protein to a more stable protein, is one of the strategies used in protein-therapeutic optimization