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Tinahones, [email protected] This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Potential Side Effects While there are no large randomized controlled studies in the injectable dosage form, some common side effects reported are injection site reactions, nausea, diarrhea, dizziness, fishy body odor, and headache
Researchers preparing nasal formulations should test stability at the target pH over the intended use period and monitor for degradation products through appropriate analytical methods
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127 SFAs, such as palmitic acid, can increase the production of ceramide and NO, leading to impaired insulin synthesis, and the apoptosis of cells through inflammation, ERS, and oxidative stress, which can be blocked by unsaturated fatty acids
