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Patients receiving vedolizumab were more likely to achieve clinical remission and endoscopic remission at 12 months

Correcting the metabolic phenotype may lead to more favorable responsiveness and cumulative pregnancy outcomes in subsequent cycles, though prospective RCT validation is still required (170, 197)

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When cells fail to respond properly to insulin, the pancreas produces more of it to compensate, leading to elevated circulating insulin levels

Treatment resistance was defined through a composite of indicators including requirement for escalation of medical therapy, progression to surgical intervention, need for CSF diversion procedures, or optic nerve decompression/ONSF necessity

less allows better absorption