This is especially concerning for patients using Wegovy or Ozempic for weight loss and diabetes management
Investigators used the TriNetX multi-institutional database to identify patients based on ICD-10 codes
Conducted in 5 countries, the study compared semaglutide 2.4 mg with placebo among 304 adults without diabetes who were obese or overweight and had at least 1 weight-related comorbidity
Neuropathol Appl Neurobio
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Upon activation, these T cells release interferon- (IFN-), which downregulates neuronal expression of ferritin heavy chain (FTH1), resulting in increased intracellular labile iron, thereby enhancing susceptibility to ferroptosis
