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For example, TNF-, IL-1, IL-6, IL-8 and IL-17A can stimulate inflammatory reactions in arthritic joints and synovial tissues (158, 188, 190), and play an important role in the development of RA

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This finding suggests that a targeted approach to enhance NAD + levels may constitute a viable strategy for preventing or treating sepsis-induced ALI (He et al

Lastly, in hypertension-prone animal models, GLP-1 infusion exerted its diuretic and natriuretic effects and resulted in a reduction of hypertension and albuminuria development, and an improved endothelial function [23]

The pattern is light-touch acknowledgment rather than active resolution, which is consistent with the BBB F rating

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