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All spectra were visually inspected prior to their inclusion in the analysis by a researcher blind to the group allocation

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Long-term use also is at risk of falling off, resulting in challenges to keep weight off

However, during clinical trials, second-generation PIs have shown better results with the fewer side effects in comparison to first-generation DAAs

Conclusion GLP-1 receptor agonists represent a paradigm shift in the treatment of metabolic diseases, combining strong clinical outcomes with significant commercial opportunity