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The medication lowers blood pressure modestly (typically 24 mmHg systolic reduction) and improves cholesterol profiles by reducing triglycerides and LDL cholesterol

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HFrEF & HFpEF Reduces the risk of cardiovascular death in adult patients and established cardiovascular disease with or without type 2 diabetes mellitus

The phase 2 trial used the same starting doses across all participants regardless of body weight, and the GI side effect profile was similar across weight categories

2009 Feb-Apr;30(1-2):42-59

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