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Even if semaglutide is already lowering your blood sugar, it may take 12 weeks or more to see changes reflected in your HbA1C test

[114] randomized subjects to semaglutide or placebo to observe the change of liver fat from baseline to week 48, and found that semaglutide significantly reduced hepatic steatosis, improved liver enzymes and metabolic parameters, and had a positive effect on the diagnosis and treatment of NAFLD compared with placebo

10.1016/j.bbadis.2022.166372 84 SannaS.van ZuydamN

touchREVIEWS in Endocrinology, 18(1), 35

Patients who arrive at a new dose already well-hydrated and fiber-sufficient handle the transition significantly better than those who try to adjust after constipation has set in