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Regeneron reports Phase 3 topline results showing up to 19.3% weight loss with dual GLP-1/GIP agonist olatorepatide in obesity trial conducted by Hansoh Pharma in China

A sub-analysis of STEP-1 showed that approximately 39% of weight lost was lean mass, consistent across age groups [3]

After you stop taking a GLP-1 RA, it will take some time for the last dose to be cleared from your system

Iwase, S

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In vivo, retatrutide produced significant reductions in body weight, adiposity, and blood glucose levels in diet-induced obese mouse models, outperforming dual GIP/GLP-1 agonists through the additional thermogenic and energy-expenditure effects mediated by glucagon receptor activation