Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1 (Vinciguerra et al., 2020
Glucagon-like peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamus
Notably, NLRP3 inflammasome activation often results in proinflammatory programmed cell death called pyroptosis, which mainly occurs in immune cell subsets, such as macrophages, monocytes and neutrophils
& Christie, M
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