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These findings further support its safety and efficacy in the treatment of EDC (Rangarajan et al., 2022)

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The goals of treatment are to reduce inflammation, eradicate infection, improve drainage and aeration of nasal and sinus mucosa, and restore mucociliary function.2 Common medical therapies for acute rhinosinusitis include antibiotics, nasal saline irrigation, decongestants, antihistamines, mucolytics, topical or systemic corticosteroids, and anti-inflammatory drugs

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Doses in the 50150 mg range exceed the general adult upper limit and can cause nausea, abdominal symptoms, copper deficiency, anemia, neutropenia and neurologic injury