Compounded GLP-1s have not been evaluated by the FDA, but side effects are expected to be similar to other GLP-1-based medications reviewed by the FDA, which have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar), flatulence (gas buildup), gastroenteritis (an intestinal infection), and gastroesophageal reflux disease (a type of digestive disorder)
Unraveling the Puzzle: Health Benefits of Probiotics a Comprehensive Review
Adverse Effects Profile (Phase 2 Data) The Phase 2 NEJM 2023 trial reported the following adverse event profile
20% of body weight) are more likely to notice hair loss with GLP-1 RA usage.[ref] Studies note that this also occurs with other forms of weight loss, like bariatric surgery, and could be tied to reduced intake of nutrients such as protein, iron, biotin, or zinc
As patient demand accelerates and care models shift toward long-term, outcomes-driven weight management, having the right operational foundation is critical
However, in Retatrutide, it is combined with GLP-1 and GIP