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Using multiple high-throughput proteomics assays in two independent cohorts of konzo-affected children compared to unrelated individuals (Discovery) or their unaffected sibling (Validation) respectively, we demonstrate that levels of the critical plasma-based antioxidant enzyme Glutathione Peroxidase 3 (GPx3) are significantly reduced in those affected
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Nelson, K.K
These drugs exert systemic effects that are crucial for a thorough understanding their safety profile, particularly in the context of obesity management
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