I dont need to be greedy
Because oral peptides must pass through the GI tract and often use absorption enhancers, they can sometimes cause localized side effects like nausea or stomach upset
Neuroimaging studies have consistently demonstrated reduced D2R availability, reflected by decreased binding potential, in key striatal and extrastriatal regions of obese individuals, supporting an association between obesity, central dopaminergic hypofunction, and dysregulated prolactin homeostasis ( 5 Mechanisms by which obesity may promote hyperprolactinemia We have systematically analyzed the potential mechanisms by which hyperprolactinemia promotes obesity
And herein lies part of the problem
Focusing only on BMI can miss important aspects of health
Based on the findings, the researchers suggest that semaglutide lowers body weight by directly interacting with diverse GLP-1R populations and directly and indirectly affecting the activity of neural pathways involved in food intake, reward, and energy expenditure