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-20C, 6 months (sealed storage, away from moisture)

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doi: 10.1097/00004836-199700001-00029 97 WallaschekNReuterSSilkenatSWolfKNiklasCKayisogluOet al

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Studies show that the C667T and A1298C variants increase the relative risk : high homocysteine, stroke, and heart disease[ref][ref][ref][ref][ref] neural tube defects and cleft lip[ref] preeclampsia and hypertension in pregnancy[ref][ref] miscarriage[ref][ref] depression or anxiety[ref][ref][ref][ref][ref] Alzheimers[ref][ref] autism spectrum disorder (C677T only according to 2026 meta-analysis)[ref] rare problems with nitrous oxide[ref], but most have no problems[ref] Lets dig into the details of what research studies and clinical trials show