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doi:10.1016/j.molmet.2019.09.010 FDA Approves New Medication for Chronic Weight Management

This distinction argues for careful long-term monitoring in peptide development programs, rather than suggesting that such risks are categorically greater than those of other modalities

In practical terms, here is what those ranges look like by body weight

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Postmarketing surveillance and observational studies have reported cases of pancreatitis in patients receiving GLP-1 receptor agonists, although a causal relationship remains debated and confounded by underlying disease risk factors ( In addition, rodent studies demonstrating thyroid C-cell hyperplasia and tumors led to class warnings and contraindications in susceptible populations