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Supplementary Video 5 (download MP4 The NTD moves upon ATP hydrolysis in D1, starting from the up position observed in the ATPS state (PDB 5FTN) 5 to the down position in ADPP i states A and B (PDB 8OOI, this work)

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References Aasi O, Alahmad Y, Beesh M, Swed A

3.4 Time to onset analysis With the exception of lixisenatide, which was excluded from the analysis due to insufficient validated data, the time to onset of metabolic and nutritional disorders was summarized in Figure 3

Yes, the treatments are equally effective and are adjusted to fit individual metabolic needs

Comprehensive impurity profiling Identifies and quantifies degradation products, variants, and contaminants