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Yes, by a modest amount

Safarinejad MR, Shafiei N, Safarinejad S (2010) The association of glutathione-S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) with idiopathic male infertility

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Patients suffering from severe heart disease, especially heart diseases such as dilated cardiomyopathy, may have severely depleted stores of ATP within heart muscle tissue

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The impressive prevalence of G6PD variants is hypothesized to be related to their conferred resistance to malaria