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Across multiple STEP trials, the enrollment criteria required a BMI of 30 or higher, or 27 or higher with at least one weight-related comorbidity (excluding type 2 diabetes, which was studied separately)

Someone already managing type 2 diabetes with a GLP-1 medication, for example, may not need a second overlapping compound and could be better served by a growth hormone pathway peptide instead

Food supplements are not a substitute for a varied and balanced diet and a healthy lifestyle

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For patients north of Alliance or out west toward Weatherford, driving to a clinic near downtown is a half-day commitment