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6,8 To date, tirzepatide has achieved an unprecedented effect on improving Hemoglobin A1c (HbA1c) and body weight in T2DM patients

Its long-acting nature reduces the risk of hypoglycemia, which has led to its gradual replacement by second-generation products such as glipizide and gliquidone

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Part of the problem Thomsen explains was 'We had underestimated the potency of liraglutide, as well as the need for slow up-titration of the drug

Guo N, Sun J, Chen H, Zhang H, Zhang Z, Cai D

The medications effects on appetite signaling and digestion are dose-dependent, meaning they become more pronounced as the dose goes up