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Vit B12 replacement therapy, typically administered intramuscularly, is the cornerstone of treatment ( 7 Heroin Heroin, chemically known as 3,6-diacetylmorphine, is a highly addictive opioid that binds to , , and opioid receptors (Waldhoer et al., 2004) undergo conformational changes upon heroin binding, thereby inhibiting adenylate cyclase activity, reducing cAMP production (Figure 3)

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Measuring 24-hour urinary magnesium excretion after an intravenous magnesium load may be used if kidney and GI function are normal

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