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An open-label, non-randomized trial in 69 patients with either type 1 or type 2 diabetes mellitus found a reduction in the incidence of muscle cramps and an improvement in the quality of life of those prescribed 0.6 g/day of L-carnitine for four months compared to controls (127)

Vitamin B12 is important for the health of your nervous system and your red blood cells

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Advanced glycation end-products (AGEs) create abnormal cross-links that stiffen collagen fibers, reducing their ability to support smooth skin and increasing brittleness that leads to deeper wrinkle formation

It also demonstrated cerebroprotective effects comparable to those of edaravone in a rat model of cerebral ischemia/reperfusion injury (Fukuta et al., 2023)