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Nowak R, Oelschlaegel U, Schuler U, Zengler H, Hofmann R, Ehninger G, Andreeff M

244 In addition, tumor cells can consume a large amount of Met in the environment by highly expressing Met transporter SLC43A2, which can inhibit the Met metabolism of T cells in the microenvironment, resulting in the loss of dimethylation of histone H3K79me2 lysine 79 in T cells, low expression of STAT5, and inhibition of T cell function

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How Tirzepatide Works in the Body Understanding the mechanism helps explain why results with this medication tend to be more significant than with earlier GLP-1 medications alone

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