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Additionally, although reporting of ASP is not a condition of CMS approving a HCPCS application, CMS has the opportunity to actively engage with the manufacturer, or sponsor of a HCPCS application, during the HCPCS application process

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The compounded market has grown significantly due to the high cost and periodic shortages of brand-name products

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For example, a review by Gwyer and colleagues (2019) concluded that while studies have reported findings across experimental models, the majority of the evidence comes from laboratory and animal research