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Following the withdrawal of albiglutide from the market in 2018 by the manufacturer for financial reasons (257), liraglutide, injectable semaglutide, and dulaglutide should currently be the preferred choices within this class for reducing cardiovascular events until further data are available (248)

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In rodent models of obesity and diabetes, liraglutide reduced myocardial TNF- expression and NF-B translocation by activating AMPK signaling (29) and augmenting myocardial glucose oxidation (30)