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32 Consequently, the FDA requested manufacturers to voluntarily withdraw their products from the market due to these safety concerns

Although these methods have demonstrated encouraging results in small-scale studies involving MS patients and EAE models, the absence of large-scale prospective randomized controlled trials means that these findings still suffer from limited reproducibility and challenges in generalizability across diverse populations

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Hence, the effects of GLP-1 RA on the central nervous system may contribute to the induction of weight loss but not necessarily to its maintenance

Common side effects include nausea, vomiting, diarrhea, or constipation, typically mild and temporary as your body adjusts