While their mechanisms of action are similar, topical acetyl hexapeptide-8 does demonstrate a lower efficacy than injected Botox, but as researchers note this is to be expected.22 Similar results were found in a small 2013 study, with the total anti-wrinkle efficacy of the Argireline treatment group being 48.9% compared to 0% in the placebo group.23 However, a more recent 2023 study investigating the effects of serum containing Argireline and hyaluronic acid found the results to be not statistically significant.24 This means that more research is needed before claims that Argireline is a true alternative to Botox can be confirmed or denied
The blood-brain barrier in aging and neurodegeneration
Scientists believe that in the near future it will be the basis for a completely new class of drugs that protect organs and treat damage within them
In particular, SG is known to be vitamin C rich, while RW was demonstrated to have antidiabetic effects (Wei et al., 2016
It exhibits an IC 50 of approximately 1 M for NNMT inhibition 4 , with favorable pharmacokinetic properties
Ethics declarations Competing Interests The authors declare no competing interests
