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Tumors and major organs, including heart, liver, spleen, lung, and kidney were isolated for pathological section analyses

However, for melasma specifically, the strongest clinical evidence supports chemical peels, laser toning, topical depigmenting agents and oral tranexamic acid

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Real world data on the epidemiology, diagnosis, and treatment of acromegaly: a registries-based approach

32 There are low rates of serious and severe infections and of malignancies in those receiving FAE, similar to or lower than with methotrexate, cyclosporine, or biologics

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