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It is not approved by the FDA for human use

Given that GS effectors have no appreciable rate of ATP turnover when supplied with canonical substrates, yet all display perfect conservation at the catalytic arginine, we infer that GS-like effectors possess a distinct catalytic activity, which may involve alternative substrate(s)

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Study protocol and informed consent, according to the Helsinki Declaration of 1975, version 2008 41 , were approved by the Regional Committee for Medical and Health Research Ethics (REC, Health Region West) (2012/2212), University of Bergen, Norway

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