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The Lancet said in an article in February: The practice of microdosing drugs is not new, but there is no evidence that it works for obesity. Ann Marie Defnet, a bariatric surgeon at Northwell Health, New York states largest healthcare provider, says in its health publication the Well: Clinical trials are where we figure out whether a treatment is both effective and safe

The FDA states that retatrutide is not a component of an FDA-approved drug and cannot be used in compounding under federal law

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[PubMed] [Google Scholar] 59.Bunzendahl H., Yin M., Stachlewitz R